重組蛋白 (Recombinant Protein)-新冠病毒(SARS-CoV2)研究-盟基生物科技股份有限公司

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新冠病毒(SARS-CoV2)研究

重組蛋白 (Recombinant Protein)

重組蛋白 (Recombinant Protein)

新冠病毒(SARS-CoV2)研究

重組蛋白 (Recombinant Protein)

提供新冠病毒的重組蛋白 (Recombinant Protein)，可以當作抗原發展抗體，或是研究病毒和細胞之間的關係。

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1. Genscript 重組蛋白
最新GenScript研發的SARS-CoV2產品型錄請點此下載

GenScript 因應新型冠狀病毒 (SARS-CoV2、2019-nCoV)，提供一系列相關重組蛋白，從完整的 S 蛋白到 RBD、ECD、S1 protein、S2 protein 一應俱全。(詳細資訊請參考原廠網頁)

(1) 新冠病毒突變株重組蛋白
變異株 蛋白 突變位點 Tag Cat. No
B.1.1.529 （South Africa) (Omicron) BA.1 Omicron BA.2 S1 Protein A67V, del69-70, T95I, G142D, del143-145, del211, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H C-terminal His Z03729 New!
S-RBD G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H C-terminal His Z03728 New!
RBD-HRP G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H C-terminal His Z03730 New!
N Protein G204R, R203K C-terminal His Z03731 New!
RBD-HRP G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H C-terminal His Z03741 New!


(2) 新冠病毒突變株重組蛋白
變異株 蛋白 突變位點 Tag Cat. No
20I/501Y.V1, VOC 202012/01, or B.1.1.7 (United Kingdom) (Alpha) S1 Protein N501Y C-terminal His Z03526
    del(69-70)   Z03523
    D614G   Z03507
    P681H   Z03527
    del(69-70)+N439K   Z03524
    del Y144   Z03522
    A222V   Z03520
    A570D   Z03521
  S-RBD N501Y C-terminal Avi & His Z03533
20H/501Y.V2 or B.1.351 (South Africa) (Beta) S1 Protein N501Y C-terminal His Z03526
    E484K   Z03529
    K417N   Z03530
    E484K+K417N+N501Y   Z03531
  S-RBD N501Y C-terminal Avi & His Z03533
    E484K   Z03535
    K417N   Z03536
    E484K+K417N+N501Y   Z03537
20J/501Y.V3 or P.1 (Brazil) (Gamma) S1 Protein E484K+K417T+N501Y C-terminal His Z03602
  S-RBD E484K+K417T+N501Y C-terminal Avi & His Z03600
20C/S:452R or B.1.429/7 (US, California) (Epsilon) S1 Protein W152C+L452R+D614G C-terminal His Z03606
  S-RBD L452R C-terminal Avi & His Z03603
20A or B.1.617 (India) S1 Protein E484Q+L452R C-terminal His Z03609
  S-RBD E484Q+L452R C-terminal Avi & His Z03607
20A/S:154K or B.1.617.1 (India) (Kappa) S1 Protein T95I+G142D+E154K+L452R+E484Q+D614G+P681R C-terminal His Z03611
20A/S:478K or B.1.617.2 (India) (Delta) S1 Protein T19R+G142D+del 156-157+R158G+L452R+T478K+D614G+P681R C-terminal His Z03612
  S-RBD L452R+T478K C-terminal Avi & His Z03613
  N Protein D63G, R203M, D377Y C-terminal His Z03732
AY.1 or B.1.617.2.1 (India) (""Delta Plus"") S-RBD K417N+L452R+T478K C-terminal Avi & His Z03689
20A or B.1.617.3 (India) S1 Protein T19R+G142D+L452R+E484Q+D614G+P681R C-terminal His Z03615
C.37 (Peru) (Lambda) S1 Protein G75V+T76I+del 247-253+L452Q+F490S C-terminal His Z03698
  S-RBD L452Q+F490S C-terminal Avi & His Z03696
B.1.1.529 (South Africa) (Omicron) BA.1 S1 Protein A67V, del69-70, T95I, G142D, del143-145, del211, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H C-terminal His Z03729
  S-RBD G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H C-terminal His Z03728
  N Protein G204R, R203K C-terminal His Z03731 New!
B.1.1.207 (Nigeria) S1 Protein Q52R+del(69-70)+E484K+ Q677H+D614G C-terminal His Z03604
Other S1 Protein N439K C-terminal His Z03525
    Y453F   Z03528
  S-RBD N439K C-terminal Avi & His Z03532
    Y453F   Z03534

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(3) 新冠病毒重組蛋白
Proteins Tag Source Cat. No. Product name
N protein tag-free E.coli Z03488 SARS-CoV-2 Nucleocapsid protein
His E.coli Z03480 SARS-CoV-2 Nucleocapsid protein (His Tag)
S-ECD His&Flag Sf9 insect cells Z03481 SARS-CoV-2 Spike protein (ECD, His & Flag Tag)
S-RBD His Sf9 insect cells Z03479 SARS-CoV-2 Spike protein (RBD, His Tag)
CHO Z03514 SARS-CoV-2 Spike protein (RBD, His Tag, CHO-expressed)
Avi&His Human Cells Z03483 SARS-CoV-2 Spike protein (RBD, His & Avi Tag)
CHO Z03512 SARS-CoV-2 Spike protein (RBD, His & Avi Tag, CHO-expressed)
Fc Human Cells Z03491 SARS-CoV-2 Spike protein (RBD, mFc Tag)
CHO Z03513 SARS-CoV-2 Spike protein (RBD, mFc Tag, CHO-expressed)
S1 protein tag-free Human Cells Z03501 SARS-CoV-2 Spike protein (S1)
His Human Cells Z03485 SARS-CoV-2 Spike protein (S1, His Tag)
CHO Z03515 SARS-CoV-2 Spike protein (S1, His Tag, CHO-expressed)
N & S-RBD Fusion His HEK293 Z03505 SARS-CoV-2 Nucleocapsid S-RBD Fusion (His Tag)
ACE-2 Fc CHO Z03516 ACE-2 Fc Chimera, Human (CHO-expressed)


2. Elabscience 重組蛋白
Elabscience 提供全系列的新冠病毒蛋白，包含 S, N, E, NSP protein，以及人類的相關蛋白。(詳細資訊請參考原廠網頁)

(1) 新冠病毒表面蛋白 Spike protein RBD，包含 wild-type 和 mutant。研究證明 RBD 會和人類的 ACE2 結合，進而感染細胞。透過序列多型性分析，RBD 具有高度多變性。在1609 SARS-CoV2 病毒株中，32個病毒株有 RBD 的突變。V367F 突變來自於法國和香港，V483A 和 G476S 突變來自於美國。而研究發現這些突變可能會增加 RBD 和人類 ACE2 的親和力。因此，這些突變有可能會影響到抗體藥和疫苗的效果。
類別 產品名稱 宿主 貨號 包裝
S-RBD wild-type Recombinant 2019-nCoV Spike Protein (RBD) HEK293 Cells PKSR030521 100µg
1mg
Recombinant 2019-nCoV S Protein (RBD, His Tag) HEK293 Cells PKSR030475 50µg
1mg
Recombinant 2019-nCoV Spike Protein (RBD, His Tag) HEK293 Cells PKSR030519 100µg
1mg
Baculovirus-Insect Cells PKSR030499 100µg
1mg
Recombinant 2019-nCoV Spike Protein, Biotinylated (RBD, His Tag) Baculovirus-Insect Cells PKSR030501 20µg
HEK293 Cells PKSR030520 20µg
Recombinant 2019-nCoV Spike Protein (RBD, Fc Tag) HEK293 Cells PKSR030518 100µg
1mg
Recombinant 2019-nCoV Spike Protein (RBD, mFc Tag) HEK293 Cells PKSR030500 100µg
1mg
Recombinant 2019-nCoV S Protein (RBD, mFc Tag) HEK293 Cells PKSR030474 50µg
1mg
Recombinant 2019-nCoV Spike Protein (RBD, rFc Tag) HEK293 Cells PKSR030522 100µg
1mg
Recombinant 2019-nCoV S Protein (RBD-SD1, His Tag) HEK293 Cells PKSR030477 50µg
1mg
Recombinant 2019-nCoV S Protein (RBD-SD1, mFc Tag) HEK293 Cells PKSR030476 50µg
1mg
Recombinant 2019-nCoV S Protein (RBD-SD1, Avi-His Tag) HEK293 Cells PKSR030478 20µg
100µg
S-RBD mutant Recombinant 2019-nCoV Spike Protein (RBD, His Tag)(V367F) HEK293 Cells PKSR030524 100µg
Recombinant 2019-nCoV Spike Protein (RBD, His Tag)(K458R) HEK293 Cells PKSR030525 100µg
Recombinant 2019-nCoV Spike Protein (RBD, His Tag)(F342L) HEK293 Cells PKSR030526 100µg
Recombinant 2019-nCoV Spike Protein (RBD, His Tag)(V483A) HEK293 Cells PKSR030527 100µg
Recombinant 2019-nCoV Spike Protein (RBD, His Tag)(A435S) HEK293 Cells PKSR030528 100µg
Recombinant 2019-nCoV Spike Protein (RBD, His Tag)(N354D) HEK293 Cells PKSR030529 100µg
Recombinant 2019-nCoV Spike Protein (RBD, mFc Tag)(V367F) HEK293 Cells PKSR030523 100µg


(2) 新冠病毒表面蛋白 spike protein (S) 和 envelope protein (E)，此部分的 spike protein 為完整 spike protein 或是其他 subunits。
類別 產品名稱 宿主 貨號 包裝
S protein Recombinant 2019-nCoV Spike Protein (His Tag) HEK293 Cells PKSR030490 1mg
Recombinant 2019-nCoV S-trimer Protein (His Tag) HEK293 Cells PKSR030489 50µg
1mg
S-NTD Recombinant 2019-nCoV S Protein (NTD, His Tag) HEK293 Cells PKSR030484 50µg
1mg
S-ECD Recombinant 2019-nCoV S1+S2 Protein (ECD, His Tag) Baculovirus-Insect Cells PKSR030498 100µg
1mg
S1 protein Recombinant 2019-nCoV S1 Protein HEK293 Cells PKSR030481 50µg
1mg
Recombinant 2019-nCoV S1 Protein (His Tag) HEK293 Cells PKSR030482 50µg
1mg
HEK293 Cells PKSR030503 100µg
1mg
Baculovirus-Insect Cells PKSR030514 100µg
1mg
Recombinant 2019-nCoV S1 Protein, Biotinylated (His Tag) HEK293 Cells PKSR030515 20µg
Recombinant 2019-nCoV S1 Protein (Fc Tag) HEK293 Cells PKSR030480 50µg
1mg
HEK293 Cells PKSR030502 100µg
1mg
Recombinant 2019-nCoV S1 Protein (mFc Tag) HEK293 Cells PKSR030479 50µg
1mg
HEK293 Cells PKSR030504 100µg
1mg
S1-CTD Recombinant 2019-nCoV S1 Protein (CTD, His Tag) HEK293 Cells PKSR030483 50µg
  1mg
S2 protein Recombinant 2019-nCoV S2 Protein (Fc Tag) HEK293 Cells PKSR030491 50µg
1mg
Recombinant 2019-nCoV S2 Protein (mFc Tag) Baculovirus-Insect Cells PKSR030516 100µg
S2-ECD Recombinant 2019-nCoV S2 Protein (ECD, His Tag) Baculovirus-Insect Cells PKSR030505 100µg
1mg
Recombinant 2019-nCoV S2 Protein (ECD, Fc Tag) HEK293 Cells PKSR030517 100µg
E protein Recombinant 2019-nCoV Envelope Protein (His Tag) E.coli PKSR030488 1mg
 

(3) 新冠病毒內部的蛋白，和病毒於細胞內部的複製相關，可以做為抑制病毒生長的目標。
類別 產品名稱 宿主 貨號 包裝
N protein Recombinant 2019-nCoV Nucleocapsid Protein (His Tag) E.coli PKSR030485 1mg
Baculovirus-Insect Cells PKSR030497 100µg
1mg
Recombinant 2019-nCoV Nucleocapsid Protein, Biotinylated (His Tag) Baculovirus-Insect Cells PKSR030512 20µg
Recombinant 2019-nCoV NP NTD domain (His Tag) E.coli PKSR030486 1mg
Recombinant 2019-nCoV NP CTD domain Protein E.coli PKSR030487 1mg
Protease Recombinant 2019-nCoV 3C-like Proteinase Protein (His Tag) E.coli PKSR030465 10μg
50μg
Recombinant 2019-nCoV Papain-Like Protease Protein E.coli PKSR030472 10μg
50μg
Recombinant 2019-nCoV Papain-like Protease Protein (His Tag) E.coli PKSR030511 100µg
1mg
Helicase Recombinant 2019-nCoV Helicase Protein (His Tag) E.coli PKSR030466 10μg
50μg
Leader protein Recombinant 2019-nCoV NSP1 Protein (His Tag) E.coli PKSR030467 10μg
50μg
p65 homolog Recombinant 2019-nCoV NSP2 Protein (His Tag) E.coli PKSR030468 10μg
50μg
Growth factor-like peptide Recombinant 2019-nCoV NSP10 Protein (His Tag) E.coli PKSR030471 10μg
50μg
Guanine-N7 methyltransferase Recombinant 2019-nCoV Guanine-N7_meth Protein (His Tag) E.coli PKSR030473 10μg
50μg
Others Recombinant 2019-nCoV NSP7 Protein (His Tag) E.coli PKSR030469 10μg
50μg
Recombinant 2019-nCoV NSP8 Protein (His Tag) E.coli PKSR030470 10μg
50μg
Recombinant 2019-nCoV Methyltransferase / ME Protein (His Tag) E. coli PKSR030513 100µg
 

(4) 人類細胞幫助病毒感染的蛋白，新冠病毒 (SARS-CoV2、2019-nCoV) 透過 S protein 結合細胞的 ACE2，並透過宿主的 Cathepsin B/L 和 CD147 降解 spike protein，幫助病毒釋放核酸進入細胞。因此 Elabscience 也有提供人類細胞和感染的相關蛋白質，幫助感染機制的研究。
類別 產品名稱 宿主 貨號 包裝
ACE-2 Recombinant Human ACE2 Protein (His Tag) HEK293 Cells PKSH032068 10μg
50μg
HEK293 Cells PKSR030508 20µg
100µg
Baculovirus-Insect Cells PKSR030510 20µg
100µg
Recombinant Human ACE2 Protein (Fc Tag) HEK293 Cells PKSR030492 10μg
50μg
Recombinant Human ACE2 Protein (mFc Tag) HEK293 Cells PKSR030494 10μg
50μg
HEK293 Cells PKSR030509 20µg
100µg
Recombinant Human ACE2 Protein (Avi-His Tag) HEK293 Cells PKSR030493 20μg
100μg
CD147 Recombinant Human CD147/Basigin Protein (His Tag) HEK293 Cells PKSH032377 10μg
50μg
Recombinant Mouse CD147/Basigin Protein (His Tag) HEK293 Cells PKSM041223 10μg
50μg
Cathepsin Recombinant Human Cathepsin B/CTSB Protein (His Tag) HEK293 Cell PKSH032179 10μg
50μg
HEK293 Cell Recombinant Mouse Cathepsin B/CTSB Protein (His Tag) HEK293 Cell PKSM040956 10μg
50μg
HEK293 Cell Recombinant Human Cathepsin L/CTSL Protein (His Tag) HEK293 Cell PKSH032182 10μg
50μg
Recombinant Mouse Cathepsin L/CTSL Protein His Tag) HEK293 Cell PKSM041247 10μg
50μg
APN Recombinant Human APN Protein (His Tag) HEK293 Cell PKSR030495 10μg
50μg
Recombinant Mouse APN Protein (His Tag) HEK293 Cell PKSR030496 10μg
50μg
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